<molecular biology> A conserved protein domain of around 150 amino acids, composed of a 20 amino acid homeobox domain and a larger POU specific domain and so is the target of some transcription factors.

Named POU (Pit Oct Unc) after 3 such proteins: Pit 1 regulates expression of certain pituitary genes, Oct 1 and 2, that bind an octamer sequence in the promoters of histone H2A and some immunoglobulin genes and Unc 86, involved in nematode sensory neurone development.

(31 Dec 1997)

pouchitis, pouch of Douglas, pouch, pavlov, pouch-shell < Prev | Next > poudrage, Poul Astrup, poulpe

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