IP3 -->
inositol 1,4,5-trisphosphate
medical dictionary


Intracellular messenger formed by the action of phospholipase c on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of b kinase or calmodulin.

Chemical name: D-myo-Inositol, 1,4,5-tris(dihydrogen phosphate)

Abbreviation: IP3

(12 Dec 1998)