Henderson-Hasselbalch equationmedical dictionary

<chemistry> The Henderson-Hasselbalch equation is the equation:

PH = pK + log ([A-]/[HA])

Where pH is the acidity or alkalinity of the buffer solution, pK is the negative logarithm of the equilibrium constant (Kd) for the ionisation of the acid form (A-) of the compound used to buffer the solution for the reaction HA = H+ +A-, [A-] is the molar concentration of the ionised form of the buffer compound, and [HA] is the molar concentration of the nonionised form of the buffer compound.

(09 Oct 1997)