DNA N-glycosidasemedical dictionary

<enzyme>

<cell biology> Excises 3-methyladenine from alkylated DNA leaving an apurinic site with both 3' and 5' phosphodiester bonds intact, a preparatory step for nucleotide excision repair; excises hypoxanthine from deaminated DNA and polydeoxyribonucleotides; prefer EC 3.2.2.20 or EC 3.2.2.21

Registry number: EC 3.2.2.-

Synonyms: DNA glycosylase, methylpurine DNA glycosylase

(26 Jun 1999)