dictionary help| 3-iodobenzylguanidine | medical dictionary |
<chemical>
A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumours. The radiolabelled forms are used as antineoplastic agent and radioactive imaging agents. mibg serves as a neurone-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.
Pharmacological action: antineoplastic agent, enzyme inhibitors, radiopharmaceuticals, sympatholytics.
(12 Dec 1998)
3-hydroxysteroid dehydrogenases, 3-hydroxytyramine, 3Hyp, 3-iodo-1,2-propanediol < Prev | Next > 3-isopropylcatechol 2,3-dioxygenase
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