17a-hydroxyprogesteronemedical dictionary

17a-Hydroxy-4-pregnen-3,20-dione;medical use is similar to that of progesterone. The acetate is an orally effective derivative, useful in conditions in which parenterally administered progesterone or the caproate is indicated; it possesses some androgenic potency and may cause virilizing changes in a female foetus. The caproate or hexanoate has essentially the same actions and uses as progesterone, but is more potent and has a longer duration of action. A precursor of the androgens and adrenocortical hormones.

(05 Mar 2000)