16,16-dimethylprostaglandin e2medical dictionary

<chemical>

(5z,11 alpha,13e,15r)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid. A synthetic prostaglandin e analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumours.

Pharmacological action: anti-ulcer agents.

Chemical name: Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11alpha,13E,15R)-

(12 Dec 1998)