12-hydroxy-5,8,10,14-eicosatetraenoic acidmedical dictionary

A lipoxygenase metabolite of arachidonic acid. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-s-hete analog has been reported to augment tumour cell metastatic potential through activation of protein kinase c.

(12 Dec 1998)